NeuroscienceScientific ReportsPeer-reviewed
Investigating the neuroprotective effect of AAV-mediated β-synuclein overexpression in a transgenic model of synucleinopathy
Dorian Sargent, Dominique Bétemps, Matthieu Drouyer…·Thierry Baron
This study investigates whether β-synuclein overexpression via AAV can inhibit α-synuclein aggregation in a synucleinopathy model, but finds no delay in disease onset and reports specific β-synuclein aggregates in treated mice.
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