DiSCs: Domains involving SETDB1 and Cohesin are critical regulators of genome topology and stem cell fate
Tushar Warrier, Chadi A. El Farran, Yingying Zeng, Benedict Shao Quan Ho, Don Loi Xu, Qiuye Bao, Zihao Zheng, Xuezhi Bi, Kelly Yu Sing Tan, Huck‐Hui Ng, Derrick Sek Tong Ong, Justin Jang Hann Chu, Amartya Sanyal, Melissa J. Fullwood, James J. Collins, , Yuin‐Han Loh
The paper identifies DiSCs, regions co-bound by SETDB1 and Cohesin, which regulate genome topology and stem cell fate in mouse embryonic stem cells.
bioRxiv · Jan 27, 2022 · PreprintGenomics