Mycn regulates intestinal development through ribosomal biogenesis in a zebrafish model of Feingold syndrome 1
Yun-Fei Li, Tao Cheng, Yingjie Zhang, Xinxin Fu, Jing Mo, Guo-Qin Zhao, Maoguang Xue, Dinghao Zhuo, Yan-Yi Xing, Ying Huang, Xiao-Zhi Sun, Dan Wang, Xiang Liu, Yang Dong, Xiao-Sheng Zhu, , Peng‐Fei Xu
This study uses a zebrafish model of Feingold syndrome 1 to show that Mycn regulates intestinal development through ribosomal biogenesis and that leucine supplementation can rescue the intestinal defect.
PLoS Biology · Nov 1, 2022Peer-reviewedDevelopmental Biology