Dinghao Zhuo

This study identifies Angptl5 as a regulator of hematopoietic homeostasis in zebrafish by modulating retinoic acid signaling, leading to myeloid hyperplasia and erythroid expansion in mutants.

The paper shows that Ripply1 and Gsc suppress anterior endoderm differentiation from prechordal plate progenitors by repressing sox32 through cis-element binding.

This study uses a zebrafish model of Feingold syndrome 1 to show that Mycn regulates intestinal development through ribosomal biogenesis and that leucine supplementation can rescue the intestinal defect.