Dichotomic Regulation of Striatal Plasticity by Dynorphin
Renzhi Yang, Rupa R. Lalchandani, Fuu-Jiun Hwang, Daniel W. Bloodgood, Dong Kong, Jun Ding
This study shows that dynorphin selectively suppresses LTP in dSPNs via KOR, and its absence enhances LTP and flexibility in reversal learning.
bioRxiv · Apr 4, 2022 · PreprintNeuroscience