Fuu-Jiun Hwang

This study shows that motor learning dynamically regulates axonal boutons in the corticostriatal pathway, increasing reward-selective boutons and eliminating un-rewarded ones.

The paper identifies region-specific transcriptomic changes in motor cortex and striatum during motor learning using single-cell RNA sequencing and genetic labeling.

The paper identifies thalamic neurons that integrate signals from the basal ganglia and cerebellum during motor learning and shows their critical role in motor task execution.

This paper introduces positively tuned GEVIs that enhance spike detection in vivo with standard imaging systems, offering higher temporal resolution than calcium indicators.

This study identifies synaptic plasticity in motor engram neurons during motor learning, showing increased spine density and connectivity to striatal neurons.

This study shows that dynorphin selectively suppresses LTP in dSPNs via KOR, and its absence enhances LTP and flexibility in reversal learning.