Biphasic impact of prenatal inflammation and macrophage depletion on the wiring of neocortical inhibitory circuits
Morgane Sonia Thion, Coralie‐Anne Mosser, Isabelle Férézou, Pauline Grisel, Sofia Baptista, Donovan Low, Florent Ginhoux, Sonia Garel, Étienne Audinat
This study shows that prenatal inflammation and macrophage depletion affect PV interneuron wiring in two distinct ways during development and adulthood, leading to altered inhibitory circuit function.
Cell Reports · Jul 1, 2019Peer-reviewedNeuroscience