Nur Amirah Binte Mohammad Yusof

Widespread dysregulation of mRNA splicing implicates RNA processing in the development and progression of Huntington's disease

This study identifies splicing dysregulation in RNA processing and neuronal function genes in early and late-stage Huntington's disease using an isogenic neuronal cell model and post-mortem data.

Ermin deficiency as an inside-out model of inflammatory dysmyelination

This study shows that Ermin deficiency causes myelin abnormalities and inflammation, leading to neurological deficits and increased susceptibility to demyelination, suggesting it as an 'inside-out' model for inflammatory dysmyelination.

Integrative analysis identifies key molecular signatures underlying neurodevelopmental deficits in Fragile X Syndrome

The paper identifies molecular signatures and neurodevelopmental abnormalities in FMRP-deficient neurons derived from isogenic FMR1 knockout human embryonic stem cells.

Manipulation of microbiota reveals altered myelination and white matter plasticity in a model of Huntington disease

The paper investigates how microbiota affects myelination and white matter plasticity in a Huntington disease mouse model, finding altered myelin thickness and oligodendrocyte numbers in germ-free conditions.