c-Myc inhibits macrophage antimycobacterial response in Mycobacterium tuberculosis infection
Edoardo Sarti, Cédric Dollé, Rebekka Wolfensberger, Katharina Kusejko, Doris Russenberger, Simon Bredl, Roberto F. Speck, Melanie Greter, Jan H. Rueschoff, Lucas Boeck, Dat Mai, Ana N. Jahn, Elizabeth S. Gold, Dong Liu, Alan H. Diercks, , Johannes Nemeth
This study shows that c-Myc inhibition enhances macrophage antimycobacterial activity and reduces MTB persistence in both in vitro and in vivo models.
The Journal of Infectious Diseases · Aug 26, 2025Peer-reviewedImmunology