Author

Douglas Alan

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 1

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Research Focus:benchmarking· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Adam BrowniD· 1 shared Andrew J. AguirreiD· 1 shared Andrew Lee HongiD· 1 shared Andrew O. GiacomelliiD· 1 shared Benjamin P. LeeiD· 1 shared Briana Fritchman· 1 shared Cory M. JohannesseniD· 1 shared David E. RootiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSystems Biology

Adam BrownORCID

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1 paper

Recent·Most cited

Defining protein variant functions using high-complexity mutagenesis libraries and enhanced mutant detection software ASMv1.0

Xiaoping Yang, Andrew Lee Hong, Ted Sharpe, Andrew O. Giacomelli, Robert E. Lintner, Douglas Alan, Thomas Green, Tikvah K. Hayes, Federica Piccioni, Briana Fritchman, Hinako Kawabe, Edith Sawyer, Luke Sprenkle, Benjamin P. Lee, Nicole S. Persky, , David E. Root

The paper introduces a method to screen large variant libraries with mutations across wide regions using improved mutant detection software, enabling accurate variant calling and counting from sequencing data.

bioRxiv · Jun 16, 2021 · PreprintSystems Biology