Author

Adam Brown

Broad InstituteORCID 0000-0002-9122-4960Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Adam Brown1 paper · Columbia University

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:variant calling· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew J. AguirreiD· 1 shared Andrew Lee HongiD· 1 shared Andrew O. GiacomelliiD· 1 shared Anne D. YoderiD· 1 shared Aziz SancariD· 1 shared Benjamin P. LeeiD· 1 shared Briana Fritchman· 1 shared Cory M. JohannesseniD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperSystems Biology

Andrew J. AguirreORCID

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2 papers

Recent·Most cited

Comparative analyses of two primate species diverged by more than 60 million years show different rates but similar distribution of genome-wide UV repair events

Ümit Akköse, Veysel Oğulcan Kaya, Laura A. Lindsey‐Boltz, Zeynep Karagoz, Adam Brown, Peter A. Larsen, Anne D. Yoder, Aziz Sancar, Ogün Adebalı

The paper compares UV repair efficiency and patterns between humans and mouse lemurs, finding similar repair mechanisms but differences in efficiency.

BMC Genomics · Aug 6, 2021Peer-reviewedGenomics

Defining protein variant functions using high-complexity mutagenesis libraries and enhanced mutant detection software ASMv1.0

Xiaoping Yang, Andrew Lee Hong, Ted Sharpe, Andrew O. Giacomelli, Robert E. Lintner, Douglas Alan, Thomas Green, Tikvah K. Hayes, Federica Piccioni, Briana Fritchman, Hinako Kawabe, Edith Sawyer, Luke Sprenkle, Benjamin P. Lee, Nicole S. Persky, , David E. Root

The paper introduces a method to screen large variant libraries with mutations across wide regions using improved mutant detection software, enabling accurate variant calling and counting from sequencing data.

bioRxiv · Jun 16, 2021 · PreprintSystems Biology