Evolutionary tuning of complexin-synaptotagmin fusion clamp governs regulated neurotransmitter release
Yuanmo Wang, Dipayan Bose, Douglas Griffith, Jeremy S. Dittman, Shyam Sundar Krishnakumar
The paper compares mammalian and C. elegans orthologs of Synaptotagmin-1 and Complexin in a single-vesicle assay to understand their roles in synaptic vesicle clamping and neurotransmitter release.
bioRxiv · Oct 30, 2026 · PreprintNeuroscience