The paper compares mammalian and C. elegans orthologs of Synaptotagmin-1 and Complexin in a single-vesicle assay to understand their roles in synaptic vesicle clamping and neurotransmitter release.

DOI 10.64898/2026.10.26.761994

C. eleganshuman

𝕏 PostBluesky

MicrobiologybioRxivPreprintOct 29, 2026

Kinetochore Proteins CENPB and LIC2 are critical for Episome Persistence and Replication of Kaposis's Sarcoma-Associated Herpesvirus

Rajnish Kumar Singh, Shengwei Zhang, Dipayan Bose…·Erle S. Robertson

This study identifies CENPB and LIC2 as critical kinetochore proteins required for KSHV episome persistence and replication through a shRNA-based screen of kinetochore-associated genes.

DOI 10.64898/2026.10.28.762626

humanexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 15, 2024

A minimal presynaptic protein machinery mediating synchronous and asynchronous exocytosis and short-term plasticity.

Dipayan Bose, Manindra Bera, Christopher A. Norman…·Shyam Sundar Krishnakumar

The paper identifies a minimal set of presynaptic proteins that regulate different modes of Ca2+-triggered vesicle fusion and short-term plasticity.

DOI 10.1101/2024.04.15.589559

experimental assay

𝕏 PostBluesky