BiophysicsBiophysical JournalPeer-reviewed
On the Mechanism of Ezrin Activation
Dovydas Vasiliauskas, Jeriann R. Beiter, Sahithya Sridharan Iyer…·Gregory A. Voth
This study reveals that ezrin activation involves spontaneous FERM-CTD dissociation triggered by PI(4,5)P2 binding, with phosphorylation stabilizing the open conformation.
3 citations