Sahithya Sridharan Iyer

This study compares Zyxin and LPP's mechanoaccumulation at tricellular junctions under tension, revealing differences in their LIM domain sensing mechanisms.

The paper uses molecular dynamics simulations to show that phosphate release from actin filaments is limited by dissociation from Mg2+ and varies with subunit position and water molecule count.

This study reveals that ezrin activation involves spontaneous FERM-CTD dissociation triggered by PI(4,5)P2 binding, with phosphorylation stabilizing the open conformation.

This paper uses molecular dynamics simulations at 310 K to analyze cryo-EM reconstructions of actin filaments, revealing conformational differences from physiological conditions and explaining functional properties.

This paper uses simulations to show that highly ordered lipid bilayers exhibit glass-like dynamics with soft fluid channels, which may facilitate molecular interactions.