Author

Duanchen Ding

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Rongrong Xiao· 2 shared Xiaoni AiiD· 2 shared Yu Zhou· 2 shared Fan Zhang· 1 shared Feng Zhang· 1 shared Jian WangiD· 1 shared Jianchuang Liu· 1 shared Q Liu· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

Rongrong Xiao

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2 papers

Recent·Most cited

A colorectal cancer organoid-CAF co-culture chip for drug screening and personalized therapy

Rongrong Xiao, Zhijie Wang, Yu Zhou, Duanchen Ding, Jian Wang, Jianchuang Liu, Yi Wang, Q Liu, Xiaoni Ai

This paper develops a co-culture chip to model colorectal cancer TME with CAFs, showing improved drug response prediction and tumor recurrence compared to organoid-only models.

bioRxiv · Jun 19, 2026 · PreprintCell Biology

A hybrid framework integrating structural machine learning and 3D liver-on-chip assay for drug-induced liver injury prediction

Fan Zhang, Yu Zhou, Duanchen Ding, Feng Zhang, Rongrong Xiao, Xiaoni Ai

Oakuloid combines a structural machine learning model with a 3D liver-on-chip assay to predict drug-induced liver injury, achieving high AUROC on external benchmarks and offering orthogonal confirmation signals.

bioRxiv · Jun 18, 2026 · PreprintBiochemistry