Author

Zhijie Wang

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0002-7722-4956Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Zhijie Wang1 paper · Inner Mongolia University

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Jianchun DuaniD· 2 shared Jie WangiD· 2 shared Chunwei XuiD· 1 shared Danming HeiD· 1 shared Duanchen Ding· 1 shared Guoqiang WangiD· 1 shared Hua Bai· 1 shared Huafei Lu· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersCancer Biology

Jianchun DuanORCID

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Author profile →

3 papers

Recent·Most cited

Co-targeting KRAS and BCL-2 induces pyroptosis and antitumor tertiary lymphoid structures

Xu Yang, Man Li, Jian Zhang, Danming He, Xu Liu, Lihui Liu, Jianchun Duan, Zhijie Wang, Hua Bai, Jie Wang

This study shows that combining KRAS and BCL-2 inhibition induces pyroptosis and tertiary lymphoid structures in KRAS G12D-mutant lung cancer, enhancing B-cell-dependent antitumor immunity.

bioRxiv · Oct 14, 2026 · PreprintCancer Biology

A colorectal cancer organoid-CAF co-culture chip for drug screening and personalized therapy

Rongrong Xiao, Zhijie Wang, Yu Zhou, Duanchen Ding, Jian Wang, Jianchuang Liu, Yi Wang, Q Liu, Xiaoni Ai

This paper develops a co-culture chip to model colorectal cancer TME with CAFs, showing improved drug response prediction and tumor recurrence compared to organoid-only models.

bioRxiv · Jun 19, 2026 · PreprintCell Biology

IMPACT: a web server for exploring immunotherapeutic predictive and cancer prognostic biomarkers

Yutao Liu, Yundi Zhang, Wenchuan Xie, Jing Zhao, Yiting Dong, Chunwei Xu, Yanan Wang, Man Li, Guoqiang Wang, Zhu Xin, Wenxian Wang, Kequan Lin, Huafei Lu, Yusheng Han, Leo Li, , Zhijie Wang

IMPACT is a web server that explores immunotherapeutic predictive and cancer prognostic biomarkers using a large dataset of 6,276 patients treated with immune checkpoint inhibitors.

Clinical and Translational Medicine · Aug 30, 2023Peer-reviewedBioinformatics