Early steps of the biosynthesis of the anticancer antibiotic pleurotin
Jack A. Weaver, Duha Alkhder, Panward Prasongpholchai, Michaël D. Tadesse, Emmanuel L. C. de los Santos, Lijiang Song, Christophe Corre, Fabrizio Alberti
This study identifies the origin of the quinone ring in pleurotin and characterizes a biosynthetic intermediate using genome sequencing and heterologous expression.
ACS Chemical Biology · Oct 28, 2024Peer-reviewedMicrobiology