Late-Onset Preeclampsia is characterised by Accelerated Placental Aging
Anya L. Arthurs, Rudrarup Bhattacharjee, M. Smith, Dulce Medina, Ellen Melaleuca Menkhorst, German Atzin Mora-Roldan, Jessica M. Williamson, Lynda K. Harris, Jose Maria Polo, David A. MacIntyre, Claire Trelford Roberts
This study identifies oxidative stress and TERRA loss as drivers of placental aging in late-onset preeclampsia, showing antioxidant treatment can mitigate these effects.
bioRxiv · Nov 12, 2025 · PreprintDevelopmental Biology