Author

DW Crook

John Radcliffe Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Nicole E StoesseriD· 2 shared A Kasarskis· 1 shared AE Sheppard· 1 shared AJ Mathers· 1 shared Ann Sarah WalkeriD· 1 shared AS Walker· 1 shared Bede ConstantinidesiD· 1 shared David W. EyreiD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Nicole E StoesserORCID

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2 papers

Recent·Most cited

Evaluation of metagenomic, 16S rRNA gene and ultra-plexed PCR-based sequencing approaches for profiling antimicrobial resistance gene and bacterial taxonomic composition of polymicrobial samples

KK Chau, William Matlock, Bede Constantinides, Samuel Lipworth, Lindsay K. Newbold, Holly J. Tipper, Tim Goodall, Howard Brett, J Hughes, DW Crook, David W. Eyre, DS Read, Ann Sarah Walker, Nicole E Stoesser

The paper evaluates metagenomic, 16S rRNA gene, and ultra-plexed PCR-based sequencing methods for taxonomic and AMR gene profiling in polymicrobial samples, finding that AmpliSeq and shotgun metagenomics perform best for resistome profiling.

bioRxiv · May 12, 2022 · PreprintGenomics

Genomic epidemiology of global Klebsiella pneumoniae carbapenemase (KPC)-producing E. coli

N Stoesser, AE Sheppard, G Peirano, LW Anson, L Pankhurst, R Sebra, HTT Phan, A Kasarskis, AJ Mathers, TEA Peto, P Brandford, MR Motyl, AS Walker, DW Crook, JD Pitout

This study investigates the genomic spread of KPC-producing E. coli globally using whole genome sequencing, revealing diverse plasmid and mobile genetic element associations.

bioRxiv · Feb 27, 2017 · PreprintMicrobiology