ΔNp63 drives dysplastic alveolar remodeling and restricts epithelial plasticity upon severe lung injury
Aaron I. Weiner, Gan Zhao, Hanna M. Zayas, Nicolas P. Holcomb, Stephanie Adams‐Tzivelekidis, Joanna Wong, Maria Elena Gentile, Dyuthi Reddy, Joey Wei, Gargi Palashikar, Kwaku K. Quansah, Andrew E. Vaughan
This study identifies ΔNp63 as a driver of dysplastic alveolar remodeling by restricting fate plasticity of p63+ progenitors in severe lung injury.
Cell Reports · Dec 1, 2022Peer-reviewedMolecular Biology