Gan Zhao

Alveolar epithelium propagates mechanical signals that control multi-cellular homeostasis in the lung

This study shows that alveolar epithelial type I cells propagate mechanical signals that affect lung homeostasis and disease states through intercellular communication.

A longitudinal atlas of post-viral lung regeneration reveals persistent injury-associated cell states

This study maps the temporal sequence of mouse lung regeneration after viral injury, identifying persistent injury-associated cell states and their role in alveolar niche repair.

ΔNp63 drives dysplastic alveolar remodeling and restricts epithelial plasticity upon severe lung injury

This study identifies ΔNp63 as a driver of dysplastic alveolar remodeling by restricting fate plasticity of p63+ progenitors in severe lung injury.

Orthotopic Transplantation and Engraftment of Human Induced Pluripotent Stem Cell-Derived Alveolar Progenitor Cells into Murine Lungs

This paper demonstrates the orthotopic transplantation of human induced pluripotent stem cell-derived alveolar progenitor cells into murine lungs to create a humanized lung model.