ADAR1 editing dependency in triple-negative breast cancer
C.-P. Kung, K. A. Cottrell, S. Ryu, E. R. Bramel, R. D. Kladney, E. A. Bross, L. Maggi, J. D. Weber
This study shows ADAR1 is essential for TNBC cell proliferation and tumorigenesis, with its loss reducing proliferation and being rescued by IFNAR1 reduction.
bioRxiv · Jan 31, 2020Cancer Biology