Author

E. A. Outwin

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. Oberoi· 1 shared J. S. Chaudhary· 1 shared L. Pearl· 1 shared P. Schellenberger· 1 shared T. I. Roumeliotis· 1 shared X. Aran-Guiu· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

J. Oberoi

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1 paper

Recent·Most cited

HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation

L. Pearl, J. Oberoi, X. Aran-Guiu, E. A. Outwin, P. Schellenberger, T. I. Roumeliotis, J. S. Chaudhary

The paper presents cryoEM structures of HSP90-CDC37-BRAFV600E complexes with PP5, showing how PP5 dephosphorylates client kinases upon recruitment to HSP90 complexes.

bioRxiv · May 3, 2022Biochemistry