Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP2
E. A. Tungadi, A. Ito, T. Kiyomitsu, G. Goshima
This study shows that human ASPM and CDK5RAP2 redundantly function in spindle pole organisation during mitosis, with ASPM depletion alone not affecting spindle morphology but causing defects when CDK5RAP2 is also depleted.
bioRxiv · Jul 29, 2017Cell Biology