G. Goshima

Live-cell imaging under centrifugation characterized the cellular force for nuclear centration in the Caenorhabditis elegans embryo

The paper measures cellular forces for nuclear centration in C. elegans embryos using centrifugation and microscopy, finding forces increase linearly with distance and friction is reduced in microtubule mutants.

Genome sequence and cell biological toolbox of the highly regenerative, coenocytic green feather alga Bryopsis

This paper presents the genome sequence of Bryopsis, a coenocytic green alga, and identifies gene duplications and unique features that may underlie its regeneration ability.

Physcomitrella SUN2 mediates MTOC association to the nuclear envelope and facilitates chromosome alignment during spindle assembly

This study identifies SUN2 as a protein required for positioning acentrosomal MTOCs at the nuclear envelope in moss, facilitating proper chromosome alignment during spindle assembly.

Armadillo repeat-containing kinesin represents the versatile plus-end-directed transporter in Physcomitrella

This study identifies ARK as the plant-specific kinesin responsible for anterograde transport and cell tip growth in moss, with functional conservation in Arabidopsis.

Cell tip growth underlies injury response of marine macroalgae

This study investigates regeneration mechanisms in marine macroalgae after injury, finding tip cell growth and varied nuclear dynamics across species.

Mitotic spindle formation in the absence of Polo kinase

This study identifies bypass-of-essentiality (BOE) mechanisms for Polo-like kinase (Plk) in fission yeast and human cells, revealing alternative pathways for mitotic spindle formation.

Microtubule-associated proteins promote microtubule generation in the absence of γ-tubulin in human colon cancer cells

The paper identifies four microtubule-associated proteins that enable microtubule generation without γ-tubulin in human colon cancer cells.

Growth and division mode plasticity is dependent on cell density in marine-derived black yeasts

This study shows that marine-derived black yeasts switch between filamentous and budding growth modes based on cell density, unlike conventional budding yeasts.

The 3D architecture and molecular foundations of de novo centriole assembly via bicentrioles

The paper shows that moss sperm centrioles form de novo via bicentrioles with a cartwheel, involving conserved proteins, and reveals a new pathway for centriole assembly.

Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization

This study shows that cytoplasmic viscosity affects microtubule polymerization and depolymerization rates in fission yeast, moss, and mammalian cells.

Ran-GTP is non-essential to activate NuMA for spindle pole focusing, but dynamically polarizes HURP to control mitotic spindle length

This study shows that Ran-GTP is not essential for NuMA activation in spindle pole focusing but is required for HURP polarization and spindle length regulation during prometaphase.

Spindle position dictates division site during asymmetric cell division in moss

This study shows that spindle position determines division site in moss during asymmetric cell division, challenging the notion that division planes are predetermined in plants.

Novel roles of Kinesin-13 and Kinesin-8 during cell growth and division in the moss Physcomitrella patens

This study identifies divergent roles of Kinesin-13 and Kinesin-8 in microtubule dynamics, mitotic spindle formation, and tip cell growth in the moss Physcomitrella patens.

Moss Kinesin-14 KCBP accelerates chromatid motility in anaphase

This study identifies the FERM domain of moss KCBP as essential for nuclear and chloroplast positioning, and shows KCBP binds chromosomes during anaphase for their transport.

A versatile microfluidic device for highly inclined thin illumination microscopy in the moss Physcomitrella patens

This study develops a microfluidic device for HILO microscopy in moss cells, enabling long-term imaging and compound washout without disrupting cellular processes.

Fast, Efficient, and Precise Gene Editing in the Moss Physcomitrella patens

This paper develops a method for efficient gene editing in the moss Physcomitrella patens using CRISPR/Cas9 and oligonucleotide templates to generate various mutations and enable multiplex gene editing.

Kinetochore protein depletion underlies cytokinesis failure and somatic polyploidization in the moss Physcomitrella patens

The paper shows that depletion of kinetochore proteins causes cytokinesis failure and polyploidization in moss, differing from animal cells where lagging chromosomes lead to aneuploidy.

Drosophila kinesin-8 stabilises kinetochore-microtubule interaction

This study shows Drosophila kinesin-8 Klp67A stabilizes kinetochore-microtubule attachment by balancing microtubule stabilization and destabilization, with similar roles observed in human KIF18A.

KCH kinesin drives nuclear transport and cytoskeletal coalescence for tip cell growth

This study identifies KCH as a kinesin-14 family member in moss that drives nuclear transport and cytoskeletal coalescence, essential for tip cell growth.

Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP2

This study shows that human ASPM and CDK5RAP2 redundantly function in spindle pole organisation during mitosis, with ASPM depletion alone not affecting spindle morphology but causing defects when CDK5RAP2 is also depleted.

Multiple kinesin-14 family members drive microtubule minus-end-directed transport in plant cells

The paper identifies two kinesin-14 family members in plants that drive minus-end-directed transport of membranous cargoes, compensating for the absence of dynein.