E. Arnett

Timing matters in Macrophage / CD4+ T cell interactions: An agent-based model comparing Mycobacterium tuberculosis host-pathogen interactions between latently infected and naïve individuals

This paper develops an agent-based model to simulate immune responses to Mycobacterium tuberculosis infection, showing that early macrophage-CD4+ T cell interactions in latent TB infection reduce bacterial load through TNF and IFNγ mechanisms.

A new tractable method for generating Human Alveolar Macrophage Like cells in vitro to study lung inflammatory processes and diseases

This paper develops a method to generate human alveolar macrophage-like cells in vitro using lung lipids and cytokines, enabling study of lung inflammatory diseases and infections.