Author

L. S. Schlesinger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. B. Torrelles· 3 shared C. Ye· 2 shared D. Kaushal· 2 shared J. Turner· 2 shared R. Carrion· 2 shared A. Ahkter· 1 shared A. Allue Guardia· 1 shared A. Azad· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersImmunology

J. B. Torrelles

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A new tractable method for generating Human Alveolar Macrophage Like cells in vitro to study lung inflammatory processes and diseases

S. Pahari, E. Arnett, J. Simper, A. Azad, I. Guerrero-Arguero, C. Ye, H. Zhang, H. Cai, Y. Wang, Z. Lai, N. Jarvis, M. Lumbreras, D. J. Maselli-Caceres, J. I. Peters, J. B. Torrelles, , L. S. Schlesinger

This paper develops a method to generate human alveolar macrophage-like cells in vitro using lung lipids and cytokines, enabling study of lung inflammatory diseases and infections.

bioRxiv · Apr 5, 2023Immunology

Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis growth in alveolar epithelial cells and bacterial translocation into the cytosol

A. M. Olmo-Fontanez, J. M. Scordo, A. Garcia-Vilanova, D. J. Maselli, J. Peters, B. I. Restrepo, D. L. Clemens, J. Turner, L. S. Schlesinger, J. B. Torrelles

bioRxiv · May 12, 2021 · PreprintImmunology

IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection

B. A. Rosa, M. Ahmed, D. K. Singh, J. A. Choreno-Parra, J. Cole, L. A. Jimenez-Alvarez, T. S. Rodriguez-Reyna, B. Singh, O. Golzalez, R. Carrion, L. S. Schlesinger, J. Martin, J. Zuniga, M. Mitreva, S. A. Khader, D. Kaushal

This study identifies transcriptional signatures of IFN signaling and neutrophil degranulation in SARS-CoV-2 infected rhesus macaques and humans, highlighting age-related differences and shared pathways with tuberculosis.

bioRxiv · Aug 6, 2020Immunology

Lethality of SARS-CoV-2 infection in K18 human angiotensin converting enzyme 2 transgenic mice

F. Oladunni, J.-G. Park, P. Pino Tamayo, O. Gonzalez, A. Ahkter, A. Allue Guardia, A. Olmo-Fontanez, S. Gautam, A. Garcia Vilanova, C. Ye, K. Chiem, C. Headley, V. Dwivedi, L. Parodi, K. Alfson, , J. B. Torrelles

This study demonstrates that K18 hACE2 transgenic mice are susceptible to SARS-CoV-2 infection, exhibit cytokine and chemokine storms, and serve as a model for studying viral pathogenesis and therapeutic development.

bioRxiv · Jul 18, 2020Microbiology

GPR183 regulates interferons and bacterial growth during Mycobacterium tuberculosis infection: interaction with type 2 diabetes and TB disease severity

S. Bartlett, A. T. Gemiarto, M. D. Ngo, H. Sajiir, S. Hailu, R. Sinha, C. X. Foo, L. Kleynhans, H. Tshivhula, T. Webber, H. Bielefeldt-Ohmann, N. P. West, A. M. Hiemstra, C. E. MacDonald, L. von Voss Christensen, , K. Ronacher

bioRxiv · Jul 15, 2020Microbiology