Author

E. Breukink

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:bacteria (other)· 2 Organism:E. coli· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

M. Weingarth· 2 shared R. Shukla· 2 shared A. Boes· 1 shared A. J. Peoples· 1 shared A. L. Spoering· 1 shared A. M. J. J. Bonvin· 1 shared A. M. Krueger· 1 shared A. Nitti· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

M. Weingarth

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A new antibiotic from an uncultured bacterium binds to an immutable target

R. Shukla, A. J. Peoples, K. C. Ludwig, S. Maity, M. G. N. Derks, A. M. Krueger, S. de Benedetti, B. J. A. Vermeulen, R. V. Honorato, F. Grein, F. Lavore, A. M. J. J. Bonvin, U. Kubitscheck, E. Breukink, C. Achorn, , M. Weingarth

This paper discovers a new antibiotic, clovibactin, from uncultured bacteria that targets pyrophosphate in bacterial cell wall precursors, effectively killing drug-resistant pathogens without resistance.

bioRxiv · May 15, 2023 · PreprintMicrobiology

Brevibacillin 2V, a novel antimicrobial lipopeptide with an exceptional low hemolytic activity

X. Zhao, X. Wang, R. Shukla, R. Kumar, M. Weingarth, E. Breukink, O. P. Kuipers

This study identifies and characterizes brevibacillin 2V, a novel antimicrobial lipopeptide with low hemolytic activity against eukaryotic cells, showing promise for antibiotic development.

bioRxiv · Apr 11, 2021Microbiology

Real time monitoring of peptidoglycan synthesis by membrane-reconstituted penicillin binding proteins

W. Vollmer, V. M. Hernandez-Rocamora, N. Baranova, K. Peters, E. Breukink, M. Loose

The paper develops a FRET-based assay to monitor peptidoglycan synthesis in real time using membrane-reconstituted class A penicillin binding proteins from different bacteria.

bioRxiv · Aug 2, 2020Biochemistry

Biochemical and structural insights into the activation of PBP1b by the essential domain of FtsN

A. Boes, F. Kerff, R. Herman, T. Touze, E. Breukink, M. Terrak

This study identifies EFtsN as a specific activator of PBP1b, showing it binds to PBP1b and enhances its GTase activity, with structural insights into their interaction.

bioRxiv · Jun 5, 2020 · PreprintMicrobiology