Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface
L. Yang, E. C. Semmes, C. Ovies, C. Megli, S. Permar, J. B. Gilner, C. B. Coyne
The paper develops trophoblast and decidua organoids to study antiviral defenses at the maternal-fetal interface, showing differential innate immune responses and susceptibility to HCMV.
bioRxiv · Mar 29, 2021Immunology