Innate Immune Stimulation using 3D Wireframe DNA Origami
R. R. Du, E. Cedrone, M. A. Dobrovolskaia, M. Bathe
This study investigates how 3D wireframe DNA origami stimulate the TLR9 pathway, finding that multivalent CpG display enhances immune activation while bare structures do not.
bioRxiv · Jul 8, 2022Bioengineering