Author

R. R. Du

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

M. Bathe· 3 shared E.-C. Wamhoff· 2 shared A. A. Burds· 1 shared B. Neun· 1 shared C. Sanders· 1 shared E. Cedrone· 1 shared E. Edmondson· 1 shared G. A. Knappe· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBioengineering

M. Bathe

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Evaluation of non-modified wireframe DNA origami for acute toxicity and biodistribution in mice

E.-C. Wamhoff, G. A. Knappe, A. A. Burds, R. R. Du, B. Neun, S. Difilippantonio, C. Sanders, E. Edmondson, J. L. Matta, M. Dobrovolskaia, M. Bathe

This study evaluates the acute toxicity and biodistribution of non-modified wireframe DNA origami nanoparticles in mice, finding no toxicity and minimal immunotoxicity.

bioRxiv · Feb 25, 2023 · PreprintPharmacology & Toxicology

Innate Immune Stimulation using 3D Wireframe DNA Origami

R. R. Du, E. Cedrone, M. A. Dobrovolskaia, M. Bathe

This study investigates how 3D wireframe DNA origami stimulate the TLR9 pathway, finding that multivalent CpG display enhances immune activation while bare structures do not.

bioRxiv · Jul 8, 2022Bioengineering

Bioproduction of single-stranded DNA from isogenic miniphage

T. R. Shepherd, R. R. Du, H. Huang, E.-C. Wamhoff, M. Bathe

This paper demonstrates the scalable production of custom-length single-stranded DNA (cssDNA) using engineered miniphage in E. coli, enabling applications in DNA origami and archival data storage.

bioRxiv · Jan 16, 2019 · PreprintBioengineering