Molecular mechanisms regulating the pH-dependent pr/E interaction in yellow fever virus.
E. Crampon, E. Covernton, M.-C. Vaney, M. Dellarole, A. Sharma, A. Haouz, P. England, J. Lepault, S. Duquerroy, F. A. Rey, G. Barba Spaeth
This study shows that yellow fever virus pr retains high affinity for E at neutral pH, differing from other flaviviruses, and reveals a unique mechanism for pr release from mature particles.
bioRxiv · Dec 6, 2022Microbiology