The novel compensatory reciprocal interplay between neutrophils and monocytes drives cancer progression
Z. Chen, N. Soni, G. Pinero, B. Giotti, D. J. Eddins, K. E. Lindblad, J. L. Ross, N. Tsankova, D. H. Gutmann, S. Lira, A. Lujambio, E. E. B. Ghosn, A. M. Tsankov, D. Hambardzumyan
This paper shows that eliminating monocyte chemoattraction increases neutrophil infiltration in glioblastoma, promoting tumor aggression, and that targeting both monocytes and neutrophils improves survival in mouse models.
bioRxiv · Jul 21, 2022 · PreprintImmunology