Author

D. J. Eddins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Kosters· 3 shared E. Ghosn· 3 shared B. S. Dobosh· 2 shared F. E.-H. Lee· 2 shared J. Yang· 2 shared M. R. Hernandez· 2 shared R. P. Ramonell· 2 shared A. Lujambio· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

A. Kosters

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The novel compensatory reciprocal interplay between neutrophils and monocytes drives cancer progression

Z. Chen, N. Soni, G. Pinero, B. Giotti, D. J. Eddins, K. E. Lindblad, J. L. Ross, N. Tsankova, D. H. Gutmann, S. Lira, A. Lujambio, E. E. B. Ghosn, A. M. Tsankov, D. Hambardzumyan

This paper shows that eliminating monocyte chemoattraction increases neutrophil infiltration in glioblastoma, promoting tumor aggression, and that targeting both monocytes and neutrophils improves survival in mouse models.

bioRxiv · Jul 21, 2022 · PreprintImmunology

Inactivation of SARS Coronavirus 2 and COVID-19 patient samples for contemporary immunology and metabolomics studies

D. J. Eddins, L. C. Bassit, J. Chandler, N. S. Haddad, K. Musall, J. Yang, A. Kosters, B. S. Dobosh, M. R. Hernandez, R. P. Ramonell, R. M. Tirouvanziam, F. E.-H. Lee, K. Zandi, R. F. Schinazi, E. Ghosn

This paper demonstrates optimal viral inactivation methods for SARS-CoV-2 and COVID-19 patient samples to enable safe handling at lower biosafety levels while preserving downstream assay fidelity.

bioRxiv · Oct 22, 2021Microbiology

Pathogenic neutrophilia drives acute respiratory distress syndrome in severe COVID-19 patients

D. J. Eddins, J. Yang, A. Kosters, V. Giacalone, X. Pechuan, J. D. Chandler, J. Eum, B. R. Babcock, B. S. Dobosh, M. R. Hernandez, F. Abdulkhader, G. L. Collins, R. P. Ramonell, C. Moussion, D. Orlova, , E. Ghosn

The paper identifies pathogenic neutrophilia as a driver of acute respiratory distress syndrome in severe COVID-19 patients, highlighting IL-8/CXCR2-mediated neutrophil recruitment and hyperinflammation.

bioRxiv · Jun 2, 2021 · PreprintImmunology

Hematopoietic stem cell requirement for macrophage regeneration is tissue-specific

D. J. Eddins, A. Kosters, J. Waters, J. Sosa, M. Phillips, K. Yadava, L. A. Herzenberg, H. F. Kuipers, E. Ghosn

The paper shows that hematopoietic stem cells (HSCs) are required for regeneration of peritoneal macrophages but not brain microglia.

bioRxiv · Apr 8, 2021Immunology