Dietary sugar and protein exert opposing effects on key larval growth and metabolic regulators, the Drosophila insulin-like peptides Dilp2 and Dilp6.
M. Suzawa, W. K. McPherson, E. E. Van Gorder, S. Reddy, D. L. Hilovsky, C. N. Keliinui, L. A. Jamali, M. L. Bland
This study shows that dietary sugar and protein oppositely regulate Dilp2 and Dilp6 in Drosophila larvae, affecting growth and metabolism through distinct mechanisms.
bioRxiv · Dec 1, 2022 · PreprintPhysiology