Modulating Sphingosine-1-Phosphate receptors to improve chemotherapy delivery to Ewing sarcoma
E. F. MARMONTI, H. SAVAGE, A. ZHANG, C. ALVAREZ, M. MORRELL, K. SCHADLER
This study shows that modulating S1PR1 and S1PR2 improves chemotherapy delivery and efficacy in Ewing sarcoma by normalizing tumor vessel permeability.
bioRxiv · Oct 16, 2019 · PreprintCancer Biology