Lymphocytic choriomeningitis arenavirus requires cellular COPI and AP-4 complexes for efficient replication and virion production.
O. Byford, A. B. Shaw, H. N. Tse, E. J. A. A. Todd, B. Alvarez-Rodriguez, R. Hewson, J. Fontana, J. N. Barr
This study identifies COPI and AP-4 cellular complexes as essential for LCMV replication and virion production, acting in late stages of the viral life cycle.
bioRxiv · Jun 27, 2023Microbiology