R. Hewson

Lymphocytic choriomeningitis arenavirus utilises tunnelling nanotube-like intercellular connections for cell-to-cell spread

This paper shows LCMV spreads between cells via tunnelling nanotube-like structures, bypassing extracellular transmission.

Lymphocytic choriomeningitis arenavirus requires cellular COPI and AP-4 complexes for efficient replication and virion production.

This study identifies COPI and AP-4 cellular complexes as essential for LCMV replication and virion production, acting in late stages of the viral life cycle.

Novel orthonairovirus in rodents and shrews, Gabon

The paper identifies a novel orthonairovirus in small mammals from Gabon, which is genetically related to a virus linked to human neural diseases.

Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo Hemorrhagic Fever Viruses for novel therapeutic target

This study uses multi-omics approaches to analyze host-viral interactions in CCHFV infection, identifying metabolic reprogramming and interferon-mediated antiviral mechanisms as potential therapeutic targets.

A Zika vaccine based on chimpanzee adenovirus ChAdOx1 elicits lineage-transcending sterile immunity and prevents colonisation of brain and ovaries

This paper evaluates a ZIKV vaccine based on chimpanzee adenovirus ChAdOx1, showing it provides sterile immunity against both Asian and African lineages and prevents viral colonization of brain and ovaries.

Assessment of Metagenomic MinION and Illumina sequencing as an approach for the recovery of whole genome sequences of chikungunya and dengue viruses directly from clinical samples.

This study assesses metagenomic sequencing using MinION and Illumina to recover whole genomes of chikungunya and dengue viruses from clinical samples, showing high feasibility for phylogenetic analysis.