E. J. Enemark

Rare SNP in the HELB gene interferes with RPA interaction and cellular function of HELB

The paper identifies a rare SNP in the HELB gene that disrupts its interaction with RPA and affects age at natural menopause through impaired DNA repair function.

Enteroviral 2C protein is an RNA-stimulated ATPase and uses a two-step mechanism for binding to RNA and ATP

This study elucidates the biochemical mechanism of enteroviral 2C protein's ATPase activity, showing RNA stimulates ATP hydrolysis via a two-step binding mechanism.