Author

D. W. Gohara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

C. E. Cameron· 2 shared C. Yeager· 1 shared D. D. Boehr· 1 shared D. Shengjuler· 1 shared E. J. Enemark· 1 shared G. Carter· 1 shared I. M. Moustafa· 1 shared J. J. Arnold· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

C. E. Cameron

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2 papers

Recent·Most cited

Enteroviral 2C protein is an RNA-stimulated ATPase and uses a two-step mechanism for binding to RNA and ATP

C. Yeager, G. Carter, D. W. Gohara, N. H. Yennawar, E. J. Enemark, J. J. Arnold, C. E. Cameron

This study elucidates the biochemical mechanism of enteroviral 2C protein's ATPase activity, showing RNA stimulates ATP hydrolysis via a two-step binding mechanism.

bioRxiv · Sep 28, 2022Biochemistry

The RNA-binding site of poliovirus 3C protein doubles as a phosphoinositide-binding domain

D. Shengjuler, Y. M. Chan, S. Sun, I. M. Moustafa, Z.-L. Li, D. W. Gohara, M. Buck, P. S. Cremer, D. D. Boehr, C. E. Cameron

This study identifies a dual function in poliovirus 3C protein, showing it binds both RNA and phosphoinositides, with PIP binding mediated by residues also involved in RNA binding.

bioRxiv · Aug 4, 2017Biochemistry