Molecular insights into peptide agonist engagement with the PTH1 receptor
B. P. Cary, E. J. Gerrard, M. J. Belousoff, M. M. Fletcher, Y. Jiang, I. C. Russell, S. J. Piper, D. Wootten, P. M. Sexton
This study presents cryo-EM structures of the PTH1R bound to various agonists, revealing how different peptides engage the receptor and providing insights for drug design.
bioRxiv · Sep 4, 2022 · PreprintBiochemistry