Direct observation of aggregate-triggered selective autophagy
A. F. Janssen, G. Korsten, W. Nijenhuis, E. Katrukha, L. Kapitein
This study develops and applies a live-cell assay to observe and quantify the dynamics of aggrephagy, revealing key spatiotemporal features of autophagosome formation and cargo-driven initiation.
bioRxiv · Apr 21, 2021Cell Biology