Binding Site Maturation Modulated by Molecular Density Underlies Ndc80 Binding to Kinetochore Receptor CENP-T
E. V. Tarasovetc, G. B. Sissoko, A. Maiorov, A. S. Mukhina, F. I. Ataullakhanov, I. M. Cheeseman, E. L. Grishchuk
The paper shows that Ndc80 binding to CENP-T is enhanced by molecular density, with maturation of binding sites in clusters accelerating complex formation.
bioRxiv · Feb 25, 2024Biophysics