M. Chakraborty

Active prokaryotic and eukaryotic viral ecology across spatial scale in a deep-sea brine pool

The paper analyzes viral ecology in deep-sea brine pools using metagenomic and metatranscriptomic data, revealing diverse viral communities and their interactions with prokaryotic and eukaryotic hosts.

SAXS/MC studies of the mixed-folded protein Cdt1 reveal monomeric, folded over conformations

This study uses biophysical and computational methods to characterize the structure of human Cdt1, revealing 'folded over' conformations that suggest a scaffold function.

Interactions between the gut microbiome, dietary restriction, and aging in genetically diverse mice

This study investigates how the gut microbiome interacts with aging and dietary restriction in mice, finding that host genetics significantly influence microbiome features and that dietary restriction does not rejuvenate the microbiome.

Nuclear lamin A-associated proteins are required for centromere assembly

This study shows that Lamin A-associated proteins are essential for centromere assembly during mitotic exit by interacting with centromere and kinetochore proteins.

B Cells Promote T Cell Immunosenescence and Mammalian Aging Parameters

The paper identifies B cells as drivers of T cell immunosenescence and aging, showing that targeting B cells with CD20 antibodies can reverse age-related T cell dysfunction.

Wound induced small-peptide mediated signalling cascade regulated by OsPSKR, dictates balance between growth and defense in rice

The paper identifies a peptide-mediated signaling cascade in rice regulated by OsPSKR that balances growth and defense responses during wounding.

Sex-linked gene traffic underlies the acquisition of sexually dimorphic UV color vision in Heliconius butterflies

The paper identifies that sex-specific UV color vision in Heliconius butterflies evolved through gene duplication and movement to the W chromosome, leading to female-specific UVRh1 expression.

Prenatal arsenic exposure stymies gut butyrate production and enhances gut permeability in post natal life even in absence of arsenic deftly through miR122-Occludin pathway.

This study shows prenatal arsenic exposure reduces gut butyrate production and increases permeability in mice, effects reversed by butyrate supplementation through miR122-Occludin pathway modulation.

The Ndc80-Cdt1-Ska1 complex constitute a minimal processive kinetochore-microtubule coupling unit

This study identifies a minimal molecular unit composed of Ndc80, Cdt1, and Ska1 that enables processive kinetochore-microtubule coupling during mitosis.

Assessment of local potato cultivars found in Cis-Himalayan region of West Bengal through morphology and biochemical profiling

This study evaluates local potato cultivars from North Bengal for morphology and anthocyanin content to identify stable genotypes with high tuber yield and antioxidant properties.

CLASP2 stabilizes GDP-associated terminal tubulins to prevent microtubule catastrophe

This study identifies CLASP2's mechanism of stabilizing GDP-associated terminal tubulins to prevent microtubule catastrophe.

3D Reconstruction of Murine Mitochondria Exhibits Changes in Structure Across Aging Linked to the MICOS Complex

This study examines age-related changes in mitochondrial 3D structure in mouse muscle and heart tissues, linking these changes to the MICOS complex and metabolic alterations.

Heterogenous adhesion of follower cells affects tension profile and velocity of leader cells in primary keratocyte collective cell migration

The paper shows that leader cells in keratocyte collective migration have front-high tension gradients and increased velocity due to follower cells with de-adhered substrates and cell-cell attachments.

Behavioral and genomic sensory adaptations underlying the pest activity of Drosophila suzukii

This study investigates the evolutionary basis of Drosophila suzukii's egg-laying behavior by combining behavioral, genomic, and gene expression analyses with closely related species.

Predicting Chemical Shifts with Graph Neural Networks

This paper introduces graph neural networks for predicting NMR chemical shifts, achieving accuracy without feature engineering and enabling efficient predictions for diverse molecular structures.

Oligomycins Inhibit Magnaporthe oryzae Triticum and suppress wheat blast disease

This study evaluates the effects of oligomycins B and F on Magnaporthe oryzae Triticum, showing inhibition of growth, conidia formation, germination, and disease development.

Topologically associating domains and their role in the evolution of genome structure and function in Drosophila

This study examines TAD evolution in Drosophila, finding conserved TADs, enrichment of rearrangements at TAD boundaries, and selection on structural variants at TAD boundaries.

Activation of cytoplasmic dynein through microtubule crossbridging

This study shows that cytoplasmic dynein can crossbridge microtubules, enabling it to slide and polarity-sort microtubule bundles without requiring dynactin or cargo adapters.

Networks of enhancers and microRNAs drive variation in cell states

The paper identifies enhancers and microRNAs as drivers of cell state variation in embryonic stem cells, showing how they form feedback loops to generate new cell states.

Molecular requirements for transition from lateral to end-on microtubule binding and dynamic coupling

This study reconstitutes microtubule end conversion in vitro using CENP-E and Ndc80 complex, showing their roles in enabling durable microtubule plus-end association without specialized tip-binding proteins.