Single-cell RNA Profiling Identifies Diverse Cellular Responses to EWSR1-FLI1 Down-regulation in Ewing Sarcoma
R. Khoogar, E. Lawlor, M. S. Ignatius, C. Yidong, K. Kitagawa, T. Huang, P. J. Houghton
The paper uses single-cell RNA sequencing to identify distinct cellular responses to EWSR1-FLI1 down-regulation in Ewing sarcoma, revealing dormancy and stem-like features associated with drug resistance.
bioRxiv · Aug 30, 2019 · PreprintCancer Biology