Author

E. M. Alexander

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Evolutionary Biology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:fungi (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

A. F. Cisneros Caballero· 1 shared A. K. Dube· 1 shared C. Gagne-Thivierge· 1 shared C. R. Landry· 1 shared P. C. Despres· 1 shared R. Sonigara· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperEvolutionary Biology

A. F. Cisneros Caballero

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1 paper

Recent·Most cited

Asymmetrical dose-responses shape the evolutionary trade-off between antifungal resistance and nutrient use

P. C. Despres, A. F. Cisneros Caballero, E. M. Alexander, R. Sonigara, C. Gagne-Thivierge, A. K. Dube, C. R. Landry

The paper measures amino acid substitutions in yeast Fcy1 to show a trade-off between 5-FC resistance and enzyme function, with similar patterns in Cryptococcus neoformans.

bioRxiv · Nov 29, 2021Evolutionary Biology