E. M. Bruch

High resolution cryo-EM and crystallographic snapshots of the large actinobacterial 2-oxoglutarate dehydrogenase: an all-in-one fusion with unique properties

This paper presents high-resolution cryo-EM and crystallographic structures of the actinobacterial 2-oxoglutarate dehydrogenase OdhA, revealing its unique all-in-one architecture and regulatory mechanisms.

3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme

The paper reveals the 3D architecture and structural flexibility of a mycobacterial large glutamate dehydrogenase, identifying novel structural features and potential regulatory domains.

Actinobacteria challenge the paradigm: a unique protein architecture for a well-known central metabolic complex

The paper identifies a unique protein architecture in Actinobacteria's -ketoacid dehydrogenase complex, showing a reduced acetyltransferase subunit with implications for drug targets.