Author

R. Melero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:imputation· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. M. Carazo· 2 shared A. Dodu· 1 shared A. Fish· 1 shared A. Jimenez· 1 shared A. Musacchio· 1 shared A. Perrakis· 1 shared A. Tijman· 1 shared C. Huck-Iriart· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

J. M. Carazo

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A fijivirus major viroplasm protein shows RNA-stimulated ATPase activity by adopting pentameric and hexameric assemblies of dimers

G. Llauger, R. Melero, D. Monti, G. Sycz, C. Huck-Iriart, M. L. Cerutti, S. Klinke, E. Mikkelsen, A. Tijman, R. Arranz, V. Alfonso, S. M. Arellano, F. A. Goldbaum, Y. G. J. Sterckx, J.-M. Carazo, , L. H. Otero

This study identifies the structural and functional roles of the C-arm in the fijivirus P9-1 protein, revealing its role in viroplasm assembly and RNA-stimulated ATPase activity.

bioRxiv · Apr 16, 2022Biochemistry

3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme

M. Lazaro, R. Melero, C. Huet, J. P. Lopez-Alonso, S. Delgado, A. Dodu, E. M. Bruch, L. A. Abriata, P. M. Alzari, M. Valle, M.-N. Lisa

The paper reveals the 3D architecture and structural flexibility of a mycobacterial large glutamate dehydrogenase, identifying novel structural features and potential regulatory domains.

Communications Biology · Jun 3, 2021Peer-reviewedMicrobiology

Automatic local resolution-based sharpening of cryo-EM maps.

E. Ramirez-Aportela, J. L. Vilas, R. Melero, P. Conesa, M. Martinez, D. Maluenda, J. Mota, A. Jimenez, J. Vargas, R. Marabini, J. M. Carazo, C. O. S. Sorzano

This paper introduces a new automatic method for sharpening cryo-EM maps based on local resolution, improving map quality and interpretability.

bioRxiv · Oct 2, 2018Biophysics

Dynamic Kinetochore Size Regulation Promotes Microtubule Capture And Chromosome Biorientation In Mitosis

C. Sacristan, M. Ahmad, J. Keller, J. Fermie, V. Groenewold, E. Tromer, A. Fish, R. Melero, J. M. Carazo, J. Klumperman, A. Musacchio, A. Perrakis, G. J. Kops

The paper shows that Spindly-based dynamic regulation of kinetochore size ensures proper microtubule capture and chromosome segregation by controlling corona expansion and shedding.

bioRxiv · Mar 12, 2018Cell Biology