Author

D. Megrian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

A. M. Wehenkel· 3 shared P. M. Alzari· 3 shared M. Martinez· 2 shared A. Boyko· 1 shared A. Ducret· 1 shared A. Haouz· 1 shared A. Leyva· 1 shared A. Mechaly· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

A. M. Wehenkel

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Evolutionary plasticity and functional repurposing of the essential metabolic enzyme MoeA

D. Megrian, M. Martinez, P. M. Alzari, A. M. Wehenkel

The paper investigates how the MoeA enzyme evolved multifunctionality through evolutionary and structural analyses, showing its repurposing in both bacteria and eukaryotes for diverse roles.

bioRxiv · Jul 23, 2024Evolutionary Biology

High resolution cryo-EM and crystallographic snapshots of the large actinobacterial 2-oxoglutarate dehydrogenase: an all-in-one fusion with unique properties

L. Yang, T. Wagner, A. Mechaly, A. Boyko, E. M. Bruch, D. Megrian, F. Gubellini, P. M. Alzari, M. Bellinzoni

This paper presents high-resolution cryo-EM and crystallographic structures of the actinobacterial 2-oxoglutarate dehydrogenase OdhA, revealing its unique all-in-one architecture and regulatory mechanisms.

bioRxiv · Feb 23, 2023Biochemistry

Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation.

M. Martinez, J. Petit, A. Leyva, A. Sogues Castrejon, D. Megrian, A. Rodriguez, Q. Gaday, M. Ben Assaya, M. M. Portela, A. Haouz, A. Ducret, C. Grangeasse, P. M. Alzari, R. Duran, A. M. Wehenkel

The paper identifies two new divisome members in Corynebacteriales and shows their role in coordinating cell division and polar elongation with the divisome and elongasome.

bioRxiv · Feb 1, 2023Microbiology

SepF is the FtsZ-anchor in Archaea: implications for cell division in the Last Universal Common Ancestor

N. Pende, A. Sogues, D. Megrian, H. Palabikyan, A. Sartori-Rupp, M. Grana, S. K.- M. R. Rittmann, A. M. Wehenkel, P. Alzari, S. Gribaldo

This study identifies SepF as the FtsZ anchor in Methanobrevibacter smithii, revealing its role in archaeal cell division and evolutionary implications for LUCA.

bioRxiv · Oct 6, 2020Microbiology